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In addition, carrier-free nanoparticles GEM-CXB NPs formed by the nano self-assembly of the dual drugs gemcitabine and celecoxib, exhibit dual clearance of MDSCs and tumor cells thereby significantly enhancing antitumor effects by inducing ICD and alleviating MDSC-induced immunosuppression through MDSCs clearance (134)

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Planavila A, Redondo-Angulo I, Ribas F et al (2015) Fibroblast growth factor 21 protects the heart from oxidative stress

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